Knowledge Related to Half and Half Nail

Half and half nails (also known as "Lindsay's nails") show the proximal portion of the nail white and the distal half red, pink, or brown, with a sharp line of demarcation between the two halves.:785 Seventy percent of hemodialysis patients and 56% of renal transplant patients have at least one type of nail abnormality. Absence of lunula, splinter hemorrhage, and half and half nails were significantly more common in hemodialysis patients, while leukonychia was significantly more common in transplant patients.


• Other Related Knowledge of Hemodialysis

Selected works of Hemodialysis

Palmer, Suetonia C., Sankar D. Navaneethan, Jonathan C. Craig, David W. Johnson, Marcello Tonelli, Amit X. Garg, Fabio Pellegrini et al. "Meta-analysis: erythropoiesis-stimulating agents in patients with chronic kidney disease." Annals of internal medicine 153, no. 1 (2010): 23-33.

Palmer, Suetonia C., Sankar D. Navaneethan, Jonathan C. Craig, David W. Johnson, Marcello Tonelli, Amit X. Garg, Fabio Pellegrini et al. "Meta-analysis: erythropoiesis-stimulating agents in patients with chronic kidney disease." Annals of internal medicine 153, no. 1 (2010): 23-33.

Ravani, Pietro, Suetonia C. Palmer, Matthew J. Oliver, Robert R. Quinn, Jennifer M. MacRae, Davina J. Tai, Neesh I. Pannu et al. "Associations between hemodialysis access type and clinical outcomes: a systematic review." Journal of the American Society of Nephrology 24, no. 3 (2013): 465-473.

Palmer, Suetonia, Mariacristina Vecchio, Jonathan C. Craig, Marcello Tonelli, David W. Johnson, Antonio Nicolucci, Fabio Pellegrini et al. "Prevalence of depression in chronic kidney disease: systematic review and meta-analysis of observational studies." Kidney international 84, no. 1 (2013): 179-191.

Palmer, Suetonia C., Jonathan C. Craig, Sankar D. Navaneethan, Marcello Tonelli, Fabio Pellegrini, and Giovanni FM Strippoli. "Benefits and harms of statin therapy for persons with chronic kidney disease: a systematic review and meta-analysis." Annals of internal medicine 157, no. 4 (2012): 263.


Bioethical considerations of Hemodialysis

The development of artificial uteri and ectogenesis raises a few bioethical and legal considerations, and also has important implications for reproductive rights and the abortion debate.

Artificial uteri may expand the range of fetal viability, raising questions about the role that fetal viability plays within abortion law. Within severance theory, for example, abortion rights only include the right to remove the fetus, and do not always extend to the termination of the fetus. If transferring the fetus from a woman's womb to an artificial uterus is possible, the choice to terminate a pregnancy in this way could provide an alternative to aborting the fetus.

There are also theoretical concerns that children who develop in an artificial uterus may lack "some essential bond with their mothers that other children have"; a secondary issue to woman's rights over their own body.

In the 1970 book The Dialectic of Sex, feminist Shulamith Firestone wrote that differences in biological reproductive roles are a source of gender inequality. Firestone singled out pregnancy and childbirth, making the argument that an artificial womb would free "women from the tyranny of their reproductive biology."

Knowledge Related to Half and Half Nail 1


History of Hemodialysis

This condition was originally termed nephrogenic fibrosing dermopathy as initially only skin involvement in patients with impaired kidney function was observed, and later renamed nephrogenic systemic fibrosis to better describe its systemic nature. The term "gadolinium-associated systemic fibrosis" has also been proposed to reflect the fact that impaired kidney function is not in itself the cause of NSF.

The first cases of NSF were identified in 1997, but it was first described as an independent disease entity in 2000. In 2006, the link between NSF and gadolinium-based MRI contrast agents was made. As a result, restrictions on use of GBCAs in patients with an estimated glomerular filtration rate (a measure of kidney function) under 60 and especially under 30 mL/min/1.73 m2 have been recommended and NSF is now considered rare.

After several years of controversy, during which up to 100 Danish patients suffered gadolinium poisoning after use of the contrast agent Omniscan, the Norwegian medical company Nycomed admitted that they were aware of some dangers from using gadolinium-based agents in their product.

With both Gadopentetic acid (gadopentetate dimegulumine (Magnevist)) and Gadodiamide (Omniscan) the risk was considered to outweigh the benefits and, as a result, the EMA recommended the licence for intravenous gadopentetic acid and Gadodiamide be suspended.

Following a legally binding decision issued by The European Commission and applicable in all EU Member States (Commission decision date: 23/11/2017), Intravenous Magnevist and Omniscan is now no longer authorised for use in Europe. Magnavist is, however, still authorised in Europe as an intra-articular MR contrast medium. The authorised indication for the use of linear chelated media gadobenic acid (also known as gadobenate dimeglumine; MultiHance) and gadoxetic acid (Primovist) has been limited to delayed phase liver imaging only.


Further reading of Hemodialysis

Lakhanpal, Sharad; Ginsburg, William W.; Michet, Clement J.; Doyle, John A.; Moore, S.Breanndan (1988). "Eosinophilic fasciitis: Clinical spectrum and therapeutic response in 52 cases". Seminars in Arthritis and Rheumatism. 17 (4): 221231. doi:10.1016/0049-0172(88)90008-X. ISSN0049-0172. PMID3232080.

Barnes L, Rodnan GP, Medsger TA, Short D (August 1979). "Eosinophilic fasciitis. A pathologic study of twenty cases". The American Journal of Pathology. 96 (2): 493518. PMC2042453. PMID474708.

Doyle JA, Ginsburg WW (September 1989). "Eosinophilic fasciitis". The Medical Clinics of North America. 73 (5): 115766. doi:10.1016/S0025-7125(16)30625-3. PMID2671538.

Michet CJ, Doyle JA, Ginsburg WW (January 1981). "Eosinophilic fasciitis: report of 15 cases". Mayo Clinic Proceedings. 56 (1): 2734. PMID7453247.

Bennett, R M; Herron, A; Keogh, L (1977). "Eosinophilic fasciitis. Case report and review of the literature". Annals of the Rheumatic Diseases. 36 (4): 354359. doi:10.1136/ard.36.4.354. ISSN0003-4967. PMC1006697. PMID901033.

Falanga, Vincent; Medsger, Thomas A. (1987). "Frequency, levels, and significance of blood eosinophilia in systemic sclerosis, localized scleroderma, and eosinophilic fasciitis". Journal of the American Academy of Dermatology. 17 (4): 648656. doi:10.1016/S0190-9622(87)70251-5. ISSN0190-9622. PMID3668010.

Varga J, Khri VM (November 1997). "Eosinophilia-myalgia syndrome, eosinophilic fasciitis, and related fibrosing disorders". Current Opinion in Rheumatology. 9 (6): 56270. doi:10.1097/00002281-199711000-00013. PMID9375286.

Kent, Lawrence T.; Cramer, Stewart F.; Moskowitz, Roland W. (1981). "Eosinophilic fasciitis". Arthritis & Rheumatism. 24 (5): 677683. doi:10.1002/art.1780240508. ISSN0004-3591. PMID6972219.

Moulton SJ, Kransdorf MJ, Ginsburg WW, Abril A, Persellin S (March 2005). "Eosinophilic fasciitis: spectrum of MRI findings". AJR. American Journal of Roentgenology. 184 (3): 9758. doi:10.2214/ajr.184.3.01840975. PMID15728627.


IncumbentsEvents of Hemodialysis

Monarch: Juan Carlos I

Prime Minister: Jos Mara Aznar LpezFebruary5: Endesa and Iberdrola, two electrical companies announce that the merger process that began in October 2000 has stopped and will not be finalized.

11: 7 Technicians of the Compaa Lrica die in a traffic accident.

13: Javier Bardem is nominated for an Academy Award for his role in Julian Schnabel's film Before Night Falls, being the first Spanish actor to do so.

22: Terrorist group ETA execute a car bombing that kills two employees of the company Elektra in San Sebastin.April7: The Partido de Accin Socialista (PASOC) agrees to abandon its federal congress within the United and Alternative Left.

23: Madrid is chosen to be a World Book CapitalMay13: The EAJ-PNV/EA coalition (Basque Nationalist Party and Eusko Alkartasuna) attains a great victory during the Basque regional elections, forming a government for the next four years. Juan Jos Ibarretxe stays on as president the autonomous community of the Basque Country.

August24: Singer Joaquin Sabina suffered a minor stroke because of excessive drug use that would lead him to the brink of death.

31: After the death of twelve patients undergoing hemodialysis in Valencia, Madrid and Barcelona, The Department of Pharmacy decides granting a protective detention of a dialyzer marketed by multinational Baxter.DecemberThe Orquesta Ciudad de Almera, OCAL (City Orchestra of Almeria) is founded in the Province of Almera,


Career of Hemodialysis

Rao started working at SUNY Downstate Medical Center as a nephrologist, and because of his extensive contribution to medical literature, and services to the university, he was promoted as professor of medicine, and associate director of renal diseases. he was also the director of hemodialysis services at Kings County Hospital, and a consultant in nephrology at Brooklyn Veterans Administration Hospital. He has published more than 130 scientific articles and chapters in text books. He is the founding member, past president, board of trustees, and CME chairman of the American Association of Physicians of Queens and Long Island chapter.

Rao was the nephrologist who cared for Jayaprakash Narayan when he visited the United States. He was also nephrologist in charge of Honorable M. G. Ramachandran, Chief Minister of Tamil Nadu, and Honorable Chenna Reddy, Chief Minister of Andrapradesh, both of whom underwent renal Organ transplantation at Downstate Medical Center in United States. He was also consultant for the Governor of Pondicherry who suffered renal insufficiency.

For his achievements he has been awarded honorary degrees from Madras University, and Manipal University. He is also honorary visiting professor at Rajiv Gandhi University in Karnataka state..y of Nephrology, Indian Association of Long Island, and Bangalore Medical College Alumni Association. He has delivered scientific lectures in Japan, Israel, Paris, Holland, India and other countries.

He has been honored by Indian Society of Nephrology, American Nephrologists of Indian Origin, Nassau County of NY,

Knowledge Related to Half and Half Nail 2


Education of Hemodialysis

His early schooling was in Channapatna, Karnataka. He graduated from high school in First Class, establishing a record for highest marks scored in Channapatna, and in the top 15 in Karnataka State. He graduated in First Class in Pre-University studies at National College in Bangalore, and was admitted to Bangalore Medical College. He stayed in Ramakrishna Vidhyarthi Mandiram throughout his student career. He completed his Medical degree from Bangalore Medical College as the top student with 5 gold medals. After completing one year of House Surgeoncy, he left for United States in June 1967. He completed 4 years of Medical Residency at New Jersey College of Medicine hospitals in Newark and East Orange, N.J. From 1971 to 1973, he was a fellow in Renal Medicine at State University of New York (SUNY), Downstate Medical Center and Kings County Hospitals. After passing the American Board of Internal Medicine, he was awarded a fellowship from the American College of Physicians. Subsequently, he was also board certified in the sub-specialty of Nephrology. During his fellowship he published his original work on heroin-associated nephropathy in the prestigious New England Journal of Medicine. In 1984, he described for the first time renal disease in patients with acquired immunodeficiency syndrome (AIDS). His original work AIDS Associated Nephropathy was published in the New England Journal of Medicine in 1984


Diagnosis of Hemodialysis

There is no specific imaging finding for NSF, and the diagnosis is a clinicopathological one, based on presentation and histological findings.

Microscopic pathologyAt the microscopic level, NSF shows a proliferation of dermal fibroblasts and dendritic cells, thickened collagen bundles, increased elastic fibers, and deposits of mucin. More recent case reports have described the presence of sclerotic bodies (also known as elastocollagenous balls) in skin biopsies from NSF patients. While not universally present, this finding is believed to be unique to patients exposed to gadolinium, although not necessarily limited to areas involved by NSF.

Differential diagnosisThe differential diagnoses for NSF include diffuse cutaneous or limited cutaneous systemic sclerosis, scleromyxedema, lipodermatosclerosis, scleroedema diabeticorum, graft versus host disease, eosinophilic fasciitis; eosinophilia-myalgia syndrome; porphyria cutanea tarda, and other disorders. The nearly universal absence of facial skin involvement in NSF, presence of yellow plaques on the sclera of the eyes, absence of Raynauds phenomenon, and other differences in presentation can aid the proper diagnosis. History of exposure to GBCAs would favor NSF as the differential diagnosis.

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A Look at the World's Best Hemodialysis Machine China
A Look at the World's Best Hemodialysis Machine China
A dialysis machine is a medical device used to purify blood when a patient's kidneys are unable to perform their full function. Hemodialysis or peritoneal dialysis is prescribed for critical kidney conditions and / or the detection of dangerous levels of toxins in the physiological fluid, as well as pathologies. Quanta Dialysis, founded in 2008 and headquartered in Warwickshire, UK, is a medical device manufacturer developing advanced hemodialysis systems for home and clinic use. With the launch of the 4008ATM, Fresenius Medical Care aims to provide quality life-sustaining dialysis to more end-stage renal disease (ESRD) patients in China.The growth of the hemodialysis and peritoneal dialysis market is mainly driven by factors such as the growing prevalence of kidney disease, diabetes and hypertension; an increase in the number of dialysis centers; chronic kidney disease treatment initiatives; and the failure and side effects of kidney transplantation. This industry consists of two very profitable segments: the medical device industry (segment of dialysis products and consumables) and the medical services industry (segment of dialysis services). As the most populous country in the world, China is experiencing a meteoric rise in the use of medical technology [7]. “Over the past decade, China has probably made more progress in dialysis treatment than the rest of the world combined.After all, the number of patients with chronic kidney disease in China is growing especially rapidly, even when compared to other Asian countries, at more than ten percent a year. Considering the needs of Chinese patients, Fresenius Medical Care is committed to contributing to the Chinese government's Healthy China 2030 initiative, one of whose initiatives is the development of professional dialysis centers. The 4008ATM dialysis machine is a major innovation and is the joint result of a fruitful collaboration between the Fresenius Medical Care China Design Center in Shanghai and the company's research and development team in Germany. By supplying the 5008S, Fresenius Medical Care is committed to promoting home hemodialysis in China by meeting the needs of individual patients.The product is uniquely designed to meet Fresenius Medical Care’s high-quality standards, while reducing the cost of healthcare systems and meeting the needs of emerging markets. The company has introduced new digital options that allow end-stage renal disease patients to undergo dialysis comfortably at home, including the 5008S hemodialysis machine (HD) and the new automatic peritoneal dialysis (APD). Importantly, these new technologies will be supported by Fresenius Medical Cares' DiaSmart Treatment Data Management System (TDMS), which allows healthcare professionals to remotely monitor and control patients during home dialysis. In April 2020, according to a report by the professional medical journal Hemodialysis International, the first home hemodialysis was successfully performed in mainland China using the Fresenius Medical Care 5008S HD home machine. 3 Dialysis is performed independently of the patient, confirming the feasibility of this treatment. The choice of Chinese patients.At the CIIE, Fresenius Medical Care also launched an automatic peritoneal dialysis machine (APD) in China. SC is a compact, high-performance hemodialysis system that can provide clinical efficacy using the typical flow rate of traditional office machines. ...The company's dialysis products include hemodialysis machines, peritoneal circulation, dialyzers, peritoneal solutions, hemodialysis concentrates and solutions, as well as granules, blood lines, kidney medicine and water purification systems. The company's products include artificial dialysis and blood transfusion equipment, hypodermic syringes and medical glass products.Pharmaceutical and medical devices and diagnostic products touch millions of people every day, and we are your one-stop shop for medical supplies, home health supplies, and equipment.The information and analysis provided in this report is based on in-depth interviews with leaders of leading companies in the kidney dialysis and equipment industry. Referring to the Chinese national standard “Requirements for the safety of a device for hemodialysis, hemodiafiltration and hemofiltration” [9, 10], we conducted this large-scale prospective controlled multicenter study to evaluate in vivo and in vitro performance, stability and SWS-4000. Durability of dialysis machines to better understand the quality of home hemodialysis machines, facilitate their widespread use and help find what needs to be improved for them. To our knowledge, this is the first large-scale multicenter study to assess the quality of a Chinese-made hemodialysis machine, in which we fully considered the actual operating conditions of each dialysis center.The domestic SWS-4000 dialysis machine and the German-made dialysis machine (Fresenius 4008) were compared and electrolytes in maintaining the Kt/V value, URR value, dialysis-related adverse reactions, and ultrafiltration rate of hemodialysis patients. Proper dialysate concentration, heparin injection rate, blood pump flow rate and failure rate. Among AKI patients considered candidates for RRT, the survey showed that 15.1% (95% CI, 12.3-17.9%) did not actually receive dialysis in Chinese hospitals. For patients with AKI who are considered candidates for RRT, survey participants estimated that 15.1% (95% CI, 12.3-17.9%) did not receive dialysis. The survey showed that 15% of Chinese AKI patients who were recognized as candidates for RRT for clinical reasons did not receive dialysis.Kliger said that in this subgroup of severely positive cases, the number of people requiring dialysis ranged from 20% to 40%. The medical equipment used in hemodialysis treatment may pose additional risks, including air entering the bloodstream and blood loss due to clotting or accidental disconnection of blood tubing devices. If the doctor and the qualified patient agree that it is only suitable for home hemodialysis, the use of the NxStage system for home hemodialysis during waking hours may not require the help of a partner.On the other hand, both CRRT and intermittent treatments are performed by nephrologists outside the ICU in a hospital ward with an integrated dialysis unit. But testing the device in a controlled hospital environment is very different from using it in everyday life, says Arsia Ghaffari, a researcher who leads dialysis services at the University of Southern California at Los Angeles. Dialysis does not mimic the complex structure of the human kidney, and improved, more portable versions will require miniature components and a significant reduction in the amount of water required.Another issue is how to balance the use of dialysis machines for coronavirus patients with the needs of the more than 500,000 Americans with kidney disease who already rely on dialysis machines. Currently, hospital reimbursement and patient out-of-pocket policies vary widely across the country [37], which makes some patients and their families make very difficult decisions about medical technologies that may save lives. Not all patients experience the claimed benefits of home hemodialysis (HHD).But as the disease begins to appear to be related to kidney problems, a new set of ethical questions arise about who gets treatment and who doesn't - and Uddin's case illustrates fears that an otherwise potentially preventable death could be due to shortage. dialysis. equipment. ... But at the badly damaged New York hospital where Uddin was treated, his family says all dialysis machines have already been used, which experts say is a sign of a growing link between COVID-19 and children's problems.
Know About Hemodialysis
Know About Hemodialysis
An Introduction to HemodialysisHospital General de la Plaza de la Salud (HGPS) is a non-profit entity with self-management in the selection and recruitment of staff and in the formulation and use of its budget. It is located on Avenida Ortega y Gasset Ensanche La Fe, Santo Domingo, Distrito Nacional of the Dominican Republic.The HGPS is technically and administratively managed by a board set up by Decree No. 131, April 18, 1996 and ratified by Congress through Law No.78-99, dated 24 July 1999. The Board is composed of distinguished doctors, businessmen, and individuals dedicated to serving the Dominican community as well as ex officio members: the Secretary of State for Public Health and Social Welfare, the Director of the Dominican Social Security Institute, the Chairman of National Council of Businessmen and the Secretary of Labor.Under the supervision of the Board, the HGPS has an organizational structure headed by the Executive Directorate, responsible for coordinating the planning and management to achieve its goals. Dependent on this Directorate are the Financial Management and Administration Directorate, Medical Directorate and the Directorate of Hospital Support. These in turn have different departments headed by managers and service units under the supervision of their heads.HGPS medical staff is composed of specialists, sub-specialists and general or internal practitioners, grouped into the following departments: Internal medicine and specialties, General Surgery and specialties, OB-GYN, Gastroenterology and Endoscopy, Pediatrics and specialties, Family Medicine Education and Research, Orthopedics and Traumatology. Other services offered are: Diagnostic Imaging, Pathology, Geriatrics, Physical medicine and rehabilitation, Dentistry, Laboratory and Blood Bank, Cardiology, Onco Hematology, Ophthalmology, Breast Pathology, Emergency Medicine, nursing, pharmacy, nutrition and social work.Each year, the HGPS benefits more than 13,000 low-income patients who receive up to a 40 percent discount or are exempt from payment according to their financial condition. The HGPS receives a grant from the Dominican Government that covers the annual cost of exemptions and discounts to patients with limited resources.Since 2003, the HGPS is a teaching facility and has three medical residency programs in the areas of Family and Community Medicine, Medical Emergency and Disasters and Rehabilitation Medicine, supported by the Universidad Iberoamericana (UNIBE). At present, the HGPS has become a major center for training and education for the health sciences faculties of major universities in the country: UNIBE, INTEC, UNPHU, UCE, UASD, and the Catholic University Santo Domingo (UCSD), for both its undergraduate and graduate programs.The HGPS is recognized as a center of excellence in Dominican medicine, setting quality standards for the entire country.Criticism of HemodialysisSince its inception, the HGPS has been perceived by the Dominican people as being a State-run facility that should offer free services as it was initially built using State funds. However, by decree, the HGPS was created to provide non-profit medical assistance and uses the fees for services to continue to run its day-to-day operations. While the HGPS receives a government grant to cover services offered to low-income patients at discount or free of charge, the cost of operations can only be met charging a below market fee for its renown medical services.HGPS Highlights of HemodialysisIt has helped more than 140,000 low-income patients with discounts and waivers of its health treatment plans, helping to improve their quality of life and their physical and emotional well-being.Blood Bank with a high level of reliability and credibility, as well as the creation of the section of Cryopreservation of stem cells at the Blood Bank, which supports the HGPS's bone marrow transplant services (only one in the country).It is a teaching hospital facility with a board of educational programs in the following specialties: Family and Community Medicine, Medical Emergency and Disasters and Rehabilitation Medicine.Conducts a yearly Scientific Symposium to present the institution's research and medical advances.CENTOX, the first Poison control center in the Dominican Republic.Followed the successful pregnancy, delivery and birth of the first sextuplets in the Dominican Republic with only 26 and a half weeks of gestation. The children are now 4 years of age and healthy (2009).Pediatric intensive care unit (PICU) as a national reference of care.Pacemaker ClinicHemodialysis UnitCenter for Integrated medicineThorax Pain UnitOrgan and tissue transplantation program., which has a Transplant Counsel and an Organ Captivity Coordination Unit. The program achieved the first kidney transplant from a deceased donor in the country, liver transplants from deceased donors and corneal transplantation.Physical Medicine and Rehabilitation Hospital, with Urodynamics and Isokinetic Diagnostics units.Volunteerism unit to work with the hospital community with a high degree of solidarity and commitment.First Primary Care Center of the Dominican Republic.The country's first outpatient surgery program.The permanence of the only functioning hospital bioethics committee in the country, meeting regularly since 1997.Implementation of the first free hip and knee replacement program in the country called Operation Walk, a medical mission for patients with limited resources. It was led by a team of local and international specialists from Brigham and Women's Hospital and since 2008, has benefited over 80 Dominican patients and their families.Units of Care and Solidarity (UNASOL), offering medical assistance to thousands of people affected by tragedies of force majeure.Diabetic foot Clinic to prevent and treat all foot diseases in any patient.Dengue Clinic, as a national reference for all those who present symptoms.
Brief Analysis of the Importance of Preventive Maintenance Management on Medical Equipment
Brief Analysis of the Importance of Preventive Maintenance Management on Medical Equipment
  Author:MeCan Medical–ultrasound machine manufacturersThe hospital's modernization is inseparable from various advanced medical equipment, and the use of advanced medical equipment helps doctors to better judge the patient's condition. However, for medical equipment, high precision, high -priced, complex maintenance, shorter update cycle, the installation and use environment of equipment also requires relatively high requirements.In some large hospitals, medical equipment, as a fixed assets of the hospital, occupies more than half of the total asset value, and it is undoubtedly of great significance for the management of medical equipment. Preventive maintenance of medical equipment is the basis for managing medical equipment, extending the service life of medical equipment, and improving the accuracy of medical equipment diagnosis of diseases.Therefore, it is of great significance to improve the attention of medical equipment maintenance and establish and improve the management system of medical equipment in the hospital.Preventive maintenance concept: Preventive maintenance means that within a certain cycle, the device can systematically check, detect, maintain, and replace the wear parts, so that the equipment can work normally. Through preventive maintenance, the fault rate of the equipment is reduced, the maintenance time of maintenance is reduced, and the work of various tasks will be carried out smoothly.The necessity of implementation of anti -maintenance: The maintenance of medical equipment after use is essential. The implementation of preventive maintenance is to regularly maintain medical equipment. By maintaining the equipment to familiarize the structure of the device, understand the current equipment. During the maintenance process, the maintenance personnel accurately record the important conditions such as the equipment indicator and the work parameters, and then can make a rapid judgment of the fault position after recording the contrast after the medical equipment fails.Through preventive maintenance, the situation of the easy -to -wear parts of medical equipment, timely purchase parts and replace it, thereby reducing the incidence of medical equipment failure, avoiding normal examination and treatment of patients due to medical equipment failure or medical accidents. Implementation of preventive maintenance will allow medical equipment to run for a long time in a healthy state, and the service life will be extended. If you want to know more, please pay attention to the "Prun Medical Device Network", we will regularly update some new content for everyone to browse and read.
Brief Analysis of the Current Development Status and Trend of Chinese Medical Device
Brief Analysis of the Current Development Status and Trend of Chinese Medical Device
  Author:MeCan Medical–ultrasound machine manufacturersAt present, the epidemic is still spreading globally, and international trade and economic growth have stalled. Although the exports of Chinese medical equipment remain stable as a whole, they need to be alert to relevant risks and challenges. The relevant person in charge of the Medical Institution Department of the Medical Insurance Chamber of Commerce pointed out that in the short term, due to the needs of epidemic prevention and immunity, the global market has increased its dependence on the supply chain of Chinese medical device.In the long run, the epidemic has become a catalyst for reshaping the global industrial structure. With the introduction of policies in various countries, international competition will intensify, and the competition between Chinese medical devices in the global market will be more intense.In terms of market risks, the global economic recovery will lower the ability of the international market to procure ordinary medical supplies. The surge in demand for epidemic prevention materials, coupled with the decline in the efficiency of the port work, has caused serious lag in the circulation of containers, bringing a sharp increase in international logistics costs, especially shipping. The rise in raw materials and labor costs, and the strengthening of the supervision of merchants by cross -border e -commerce platforms will further squeeze the export profits of the enterprise.In addition, due to international travel restrictions, it is difficult for engineers and sales staff to conduct promotion activities in overseas markets and after -sales service for some large -scale equipment exported equipment, and it is not conducive to market sales.Overseas market expansion also needs to focus on the impact of changes in international market regulations. For example, the European Union has implemented new medical device regulations (MDR) and in vitro diagnostic medical device regulations (IVDR), pay more attention to the clinical performance of the product, strengthen the traceability of medical device products, and pay attention to improving the transparency of patients.These will improve the management and restrictions on medical device products entering the European market accordingly, and put forward higher requirements for the industry's employees, which will bring about increased costs to Chinese export companies, extending certification cycle, and increasing compliance risks, etc. challenge.
Let's Briefly Introduce the Application of Enzymes Immune Detector in Pesticides and Food
Let's Briefly Introduce the Application of Enzymes Immune Detector in Pesticides and Food
  Author:MeCan Medical–ultrasound machine manufacturersThe enzyme missionary instrument is commonly known as the enzyme -linked immunohistic detection instrument. It can be simply divided into two categories: semi -automatic and fully automatic, but its working principles are basically the same. The core of its core is a color meter, that is, the color method is used to analyze the content of the antigen or antibody. Clinical examination, biology research, agricultural science, food and environmental science. Let me introduce the application of enzyme -linked immune detector in pesticides and food.1. Fast diagnosis of animal epidemic.The enzyme -linked immune analyzer adopts the enzyme -linked immune adsorption measurement method and the corresponding reagent with a qualitative or quantitative animal disease diagnosis. Such as: pork blue ear virus, swine fever virus, pig pseudo -rabies virus, pig pseudo -rabies virus GE protein, pig ring virus, pork type encephalitis virus, pig mouth hoof disease 3ABC protein, pig mouth hoof disease virus IgG, pork fine virus, chicken chicken, chicken Bird flu, blue tongue disease, white spot syndrome, cattle infectious pleural pneumonia, cattle plague, cotton acne, and sheep acne detection.Second, pesticide residues.Organic phosphorus pesticides are commonly used in agricultural production in my country. Common types include methylmine, dichlorvos, oxygen fruit, phosphorus, and enemies. Most of them are highly toxic pesticides. By reducing the activity of cholthyne enzymes in the body, delayed neurotoxicity is caused, thereby achieving the purpose of eliminating pests. The enzyme -linked immune detector can be used to detect the methamidine content contained in fruits and vegetables.Third, food safetyThe enzyme -linked immune analysis method uses the special nature of the antibody and the corresponding antigen to detect the antibody contained in the food based on this. The immune enzyme method is to use specific enzymes as detection tags and reaction catalysts. The use of this method can be used to effectively avoid using radioactive elements during the detection process, or to conduct orientation and quantitative analysis of the detected objects. , Chemical residue, edible oil testing, water and wine beverage analysis, condiments, edible pigment, etc.At present, more automatic enzyme -linked immune detectors can be used for qualitative detection and quantitative detection. The detection only takes a few hours. It not only reduces the labor intensity of laboratory personnel, but also greatly improves the accuracy and repeatability of the determination. This is conducive to the further commercialization of ELISA technology in detection and analysis.
How Does the Magnetic Pearl Nucleic Acid Extraction Extract Nucleic Acid and Where Is the Advantage?
How Does the Magnetic Pearl Nucleic Acid Extraction Extract Nucleic Acid and Where Is the Advantage?
  Author:MeCan Medical–ultrasound machine manufacturersAs one of the current effective epidemic prevention and control methods, nucleic acid extraction and testing are no stranger to everyone. Prior to this, the method of extracting the traditional nucleic acid was chemical cracking and cylindrical method. However, with the rapid development of gene diagnosis, genetically modified food detection, and personalized medical care, traditional nucleic acid extraction technology can no longer meet the needs of today's biotechnology. As a result, magnetic pearl nucleic acid extraction came into being.No. A commercialized reagent that used the magnetic bead method to extract DNA and successfully applied for patents in the United States appeared in 1998. The magnetic bead method first absorbs the free nucleic acid molecule to the surface of the magnetic particles by cracking the cells, while the protein and polysaccharides are left in the solution. Under the influence of the magnetic field, the magnetic particles are separated from the liquid to discard the liquid to eliminate the liquid Later, the purified nucleic acid molecules were obtained after being eluted.The magnetic bead method uses the principle of combining and dissipating the magnetic acid activity group with a magnetic granular activity group under certain conditions to avoid the loss of nucleic acid during the extraction process as much as possible, and it can also remove the interference substances in the specimen (such as hemoglobin The effects of bilirubin and lipid blood), obtain high -quality nucleic acid templates. With the development of magnetic bead method extraction technology, DNA extraction has really begun to achieve standardization, rapidness and automation.The kits based on the magnetic acid extractor of the Magnetic Pearl Method are also widely used. Nucleic acid extraction kit does not require any organic solvent and no need to repeat centrifugation. At present, it can extract high -quality DNA and RNA from full blood, serum, plasma, saliva, urine, feces, cerebrospinal fluid, tissue and cells, and shorter time. The recovery rate is higher. And it can be automated and uninvited through mechanical equipment.In addition, the principle of magnetic pearl method is safe and non -toxic, and does not use toxic reagents such as benzene and chloroform in traditional methods. Mainstream nucleic acid extraction methods at home and abroad.
What Is the Extraction Step of the Magnetic Pearl Nucleic Acid Extract Instrument and What Are the C
What Is the Extraction Step of the Magnetic Pearl Nucleic Acid Extract Instrument and What Are the C
  Author:MeCan Medical–ultrasound machine manufacturersThe nucleic acid extract instrument is a supporting nucleic acid extract reagent from the motion to complete the sample nucleic acid extraction work. In the detection of the new crown, nucleic acid extraction is a very important step. At present, the extraction principle of nucleic acid extract instruments on the market is mainly divided into two types: magnetic bead method and membrane adsorption method, of which magnetic bead method occupies the mainstream market. So, what is the extraction step of the magnetic pearl nucleic acid extract instrument?Step 1: Add samples to the cracking solution.Step 2: In the cracking solution, the rupture cells release the nucleic acid to the cracking solution to transfer the magnetic beads to the cracking solution step 3: Fully mix the nucleic acid to adsorb the specific package on the surface of the magnetic beads.Step 4: Repeat the surface of the magnetic beads to remove impurities such as the unnecessary nucleic acid, protein or salt that are not needed.Step 5: Move the magnetic beads into the eluing solution and mix it fully. The nucleic acid is falling off from the surface of the magnetic bead and dissolved into the elution buffer.The magnetic pearl nucleic acid extract instrument is matched with different types of magnetic pearl nucleic acid extract reagents, and multiple samples are operated at the same time, which automatically separate the extraction and purification DNA/RNA from multiple samples such as blood, cells, tissues, viruses. The instrument uses a special magnetic stick adsorption, transfer, and releases magnetic beads to achieve the transfer of sample/magnetic bead/nucleic acid, avoiding liquid treatment, and increasing the degree of automation.Nucleic acid detection, as an important means of screening of new crown virus screening, is expected to maintain a high position for a period of time at home and abroad. The corresponding nucleic acid extract will be very strong in a considerable period of time. The operation is automated, fast, and simple, which provides a strong guarantee for the detection of new crown nucleic acid.
What Is the Working Principle of Magnetic Pearl Nucleic Acid Extract Instrument? What Are the Charac
What Is the Working Principle of Magnetic Pearl Nucleic Acid Extract Instrument? What Are the Charac
  Author:MeCan Medical–ultrasound machine manufacturersNucleic acid extraction instrument is an instrument that uses a supporting nucleic acid extract reagent from the motion to complete the sample nucleic acid extraction work. It is widely used in various fields such as disease control centers, clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microbial testing, food safety testing, animal husbandry and molecular biology research. In fact, with the normalized management of the epidemic, the nucleic acid extract instrument, as one of the commonly used equipment tested by various hospitals, has a higher frequency and the number of purchases has continued to rise. In fact, although everyone is familiar with the term of the nucleic acid extract instrument now, but it is very familiar with the term, but it is very familiar with the term of the nucleic acid extract instrument, but it is very familiar with the term, but it is very familiar with the term. I do nt know how to work and test the method of working principles. Let s take a closer look at the editor of Prank Medical Equipment.There are many classifications of nucleic acid extract instruments. In fact, the most commonly used is magnetic bead method. How does this method work? Magnetic pearl nucleic acid extract instrument is generally divided into two types: suction method and magnetic stick method. The specific operation process is as follows:First, suction method. The extraction of nucleic acids is achieved by fixed magnetic beads and metastasis liquids. Generally, the transfer of the robotic arm is generally controlled by the operating system.1. Crack. Add a cracking solution to the sample to achieve mixing and adequate reactions of the reaction solution through mechanical exercise and heating, cell cracks, and release nucleic acids.2. Adsorption. Add magnetic beads to the sample cracking solution and mix it in full. Use magnetic beads to adsorb nucleic acid under high salt and low pH value. Under the action of magnetic fields, the magnetic beads are separated from the solution. Mo the liquid out of the waste liquid tank and abandon the head.3. Washing. Remove the external magnetic field, add the new suction head to add the washing buffer, mix it fully, remove the impurities, and remove the liquid out of the magnetic field.4. Requesting. Withdrawing the magnetic field and adding the new suction head to add the elution buffer, fully mixed, the combined nucleic acid is separated from the magnetic bead, so as to obtain a purified nucleic acid.Second, magnetic stick method. By fixed liquids, the magnetic acid is separated to achieve the separation of nucleic acids. The principle and process are the same as the pumping method. The difference is the method of separation of magnetic beads and liquids. The magnetic stick method is to separate the magnetic beads from the waste liquid through the adsorption of the magnetic rod to the next step to achieve the extraction of nucleic acid.In fact, the characteristics of this magnetic pearl nucleic acid extract instrument is that it can achieve automation, high -throughput operations, safe and reliable operations, high efficiency, and pollution -free. Therefore, it is recognized by many buyers. When choosing a nucleic acid extraction instrument equipment, no matter which type of device is selected, you must have a basic understanding of it. You cannot judge the quality of the product from the price alone. For more product details, you can consult: 400-6656 -888.
What Are the Advantages of Magnetic Pearl Nucleic Acid Extraction Instrument? Look at These 4 Points
What Are the Advantages of Magnetic Pearl Nucleic Acid Extraction Instrument? Look at These 4 Points
  Author:MeCan Medical–ultrasound machine manufacturersIn recent years, the nucleic acid extract in the principle of magnetic beads has become the mainstream nucleic acid extraction equipment. So, what are the advantages of magnetic pearl nucleic acid extract? The magnetic bead method nucleic acid extract instrument is based on the magnetic beads, using magnetic beads to adsorb nucleic acid under high salt and low pH, separates the characteristics of separation from nucleic acid under the low salt and high pH value, and then use mobile magnetic beads or transfer liquid to achieve nucleic acids. The entire extraction process.The weight of the magnetic pearl nucleic acid extract instrument is the adsorption ability of magnetic beads and nucleic acids, which directly affects the output of the extraction nucleic acid. The principle of the magnetic bead method is to crack the cell first, and then combine the nucleic acid and the magnetic bead by binding the liquid. Wash the residual protein and salt ions with the washing solution. Then separate the nucleic acid and magnetic beads.This technology can separate high -purity nucleic acids from samples such as animals and plants, body fluids, and environment. Suitable for downstream applications such as PCR, Q-PCR, molecular hybridization, sequencing, etc. Because of its highly friendly operation of magnetic beads, high nucleic acid purity, and simple automation, it has been widely used in the fields of molecular cloning, molecular hybridization, and molecular diagnosis. The specific advantages of the magnetic pearl nucleic acid extraction device are reflected:1. It can realize automation and massive operations. At present, there are hundreds of pellet nucleic acid extract instruments. The extraction time of a sample can be treated with more than a hundred samples. Perform fast and timely response.2. The operation is simple and short. The entire extraction process is only four steps, and most of them can be completed within 15-40 minutes.3. Safe and non -toxic, do not use toxic reagents such as benzene and chloroform in traditional methods to reduce damage to experimental operators.4. The specific combination of magnetic beads and nucleic acids makes the extracted nucleic acid high purity and large concentration.The magnetic pearl nucleic acid extract instrument is matched with different types of magnetic pearl nucleic acid extract reagents, and multiple samples are operated at the same time, which automatically separate the extraction and purification DNA/RNA from multiple samples such as blood, cells, tissues, viruses. The instrument uses a special magnetic stick adsorption, transfer, and releases magnetic beads to achieve the transfer of sample/magnetic bead/nucleic acid, avoiding liquid treatment, and increasing the degree of automation.The fully automatic nucleic acid extraction instrument of Proven Medical Device manufacturers is based on the magnetic rod on the magnetic rod to adsorb magnetic beads and move the magnetic beads to different reagent grooves. It can apply the extraction of nucleic acids and proteins of various samples. Just add detection samples and reagents and 96 deep -hole plates. Each independent experimental cabin can run 2 96 deep -hole plates at the same time. 24 samples. It is suitable for both a small amount of sample extraction and the high -throughput extraction required for a large amount of samples.
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